Modifying Enzymes
Carnabio Usa Inc BTN - ALK / 10UG
BTN-ALK, Cytoplasmic domain, Wild type, Amino Acid 1058-1620(end), BAG10812.1, Expressed in Insect (sf21); 10microg
Discovery Life Sciences HUM CYP2C91(ARG144)+REDUCTASE
Human CYP2C91 + P450 Reductase + Cytochrome b5 SUPERSOMES 0.5 nmole cytochrome P450 in 0.5mL This activity is catalyzed by CYP2C91 expressed from human CYP2C91 cDNA using a baculovirus expression system
Discovery Life Sciences HUM CYP2C8+REDUCTASE+B5 0.5NMO
Human CYP2C8 + P450 Reductase + Cytochrome b5 SUPERSOMES, 0.5 nmole cytochrome P450 in 0.5 ml. Store at -80degreeC Catalytic assay: paclitaxel-6(alpha)-hydroxylase activity, representative catalytic activity: 2,200 pmole/(mg x min)
AURORA BIOLABS LLC Enterokinase (EK) Activity Assay Kit,96 rxn
The Enterokinase (EK) Activity Assay Kit is a fluorogenic assay designed to quantitatively measure EK protease activity. The kit includes a specific EK substrate (Asp-Asp-Asp-Asp-Lys) conjugated to the fluorophore AFC (7-amino-4-trifluoromethylcoumarin). Upon proteolytic cleavage of the substrate by EK, free AFC is released, generating a strong fluorescent signal. The fluorescence can be detected using a microplate fluorescence reader with excitation at 365 nm and emission at 505 nm. The increase in fluorescence intensity is directly proportional to EK enzymatic activity and can be used to calculate protease activity. Purified EK protease is provided in the kit as a positive control to validate assay performance and ensure proper assay setup.
Carnabio Usa Inc TYK2/5UG/CATALYTIC
TYK2, Catalytic domain, Wild type, Amino Acid 871-1187, NP_003322.3 , Expressed in Insect (sf21); 5microg
New England Biolabs, Inc. Afu Uracil-DNA Glycosylase (UDG) – 200 units
A thermostable homolog of the E. coli Uracil-DNA Glycosylase (UDG) from Archaeoglobus fulgidus. Afu UDG catalyzes the release of free uracil from uracil-containing DNA. Afu UDG efficiently hydrolyzes uracil from single-stranded or double-stranded DNA.
Selleck Chemical LLC Cabozantinib (BMS-907351) 200mg 849217-68-1 XL184
Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3?/NF-?B signaling pathway. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Dyngo-4a 50mg 1256493-34-1
Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 ?M, 1.1??M, and 2.3 ?M for DynI (brain), DynI (rec), and DynII (rec), respectively. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
New England Biolabs, Inc. dam Methyltransferase – 500 units
dam Methyltransferase modifies the adenine residue (N6) of the sequence GATC.
Carnabio Usa Inc AMPKA1/B1/G1(PRKAA1/B1/G1)/10U
AMPK1/1/1(PRKAA1/B1/G1), Full-length, Wild type, Amino Acid 1-550, NP_006242.4, Expressed in Insect (sf21); 10microg
Carnabio Usa Inc VRK1/5UG/FULL-LENGTH
VRK1, Full-length, Wild type, Amino Acid 1-396, NP_003375.1, Expressed in E. coli; 5microg
Apexbio Technology LLC DNase I (RNase-free),1000U
DNase I (RNase-free) is an endonuclease that digests single- or double- stranded DNA, generating dinucleotide, trinucleotide, and oligonucleotide products with 5´-phosphorylated and 3´-hydroxylated ends. The activity of DNase I (RNase-free) dependent on Ca2+ and can be activated by Mg2+ or Mn2+. In the presence of Mg2+, DNase I (RNase-free) can randomly cleaves arbitrary sites of double-stranded DNA; in the presence of Mn2+, DNase I (RNase-free) can simultaneously recognize both strands of DNA and cleaves at nearly same sites. DNase I (RNase-free) can act on single stranded DNA, double stranded DNA, chromatin, and RNA: DNA hybrid strands. DNase I (RNase-free) is suitable for RNA extraction, in vitro transcription, and removal of DNA for RT-PCR experiments.Other sizes are also available. Please inqury us for quote.
ACROBiosystems The enzyme hydrolyzes the β-1,4 linkage between the core GlcNAc residues in the Fc-glycan, leaving the innermost GlcNAc intact on the Fc. It is derived from Streptococcus pyogenes and expressed in E. coli. The enzyme contains a His-tag and
EndoS is an endoglycosidase from Streptococcus pyogenes that specifically hydrolyzes N-linked glycans in the Fc-region of native IgG. It specifically deglycosylates the conserved N-glycans on the Fc region of IgG by hydrolyzing the chitobiose core (at the beta -1,4 linkage between the two N-acetylglucosamines) of the N-glycans, cleavage leave one GlcNAc residue remaining attached to the asparagine residue on the peptide backbone.